Book Hotels in Lower Arsnicker Keys, FL

Cabins, apartments, houseboats! We offer comfortable & private vacation rentals

Save an extra 10% or more on select hotels with Member Discounts

Access exclusive hotel deals, only with the Travelocity app

Check prices for these dates

This weekend
Next weekend

Filter by

Guest rating
Guest rating
Star rating
Payment type
Payment type
Property type
Property type
Neighborhood
Neighborhood
Traveler experience
Traveler experience
Popular locations
Popular locations
Meal plans available
Meal plans available
Property amenities
Property amenities
Accessibility
Accessibility

Top Lower Arsnicker Keys hotels

Cheeca Lodge & Spa

Cheeca Lodge & Spa

5 out of 5
81801 Overseas Highway, Mile Marker 82 Islamorada FL
Fully refundableReserve now, pay when you stay
$312 nightly
The price is $351 total per night from May 10 to May 11
$351 total
May 10 - May 11
Total with taxes and fees
This luxury resort features a private beach, a golf course, and a full-service spa. Enjoy beachfront dining and relax with sun loungers and beach umbrellas. ...
Everything

Reviewed on Apr 24, 2026

Opens in a new windowCheeca Lodge & Spa
Chesapeake Beach Resort

Chesapeake Beach Resort

3.5 out of 5
83409 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$232 nightly
The price is $261 total per night from May 10 to May 11
$261 total
May 10 - May 11
Total with taxes and fees
A private beach, a marina, and 2 outdoor pools are all featured at this smoke-free hotel. Enjoy a day at the beach kayaking, or relax with sun loungers. Unwind ...
Friendly staff, clean property, nice views. Within walking distance to Wahoos!

Reviewed on Apr 24, 2026

Opens in a new windowChesapeake Beach Resort
Lime Tree Bay Resort

Lime Tree Bay Resort

3.5 out of 5
68500 Overseas Hwy Long Key FL
Fully refundableReserve now, pay when you stay
$205 nightly
The price is $231 total per night from May 19 to May 20
$231 total
May 19 - May 20
Total with taxes and fees
This resort features a private beach, 3 outdoor pools, and a restaurant. Business travelers can take advantage of the free WiFi in public areas. Enjoy the outdoor ...
We liked everything about it and would recommend it to anyone.

Reviewed on Apr 24, 2026

Opens in a new windowLime Tree Bay Resort
Islander Resort

Islander Resort

4 out of 5
82100 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$298 nightly
The price is $335 total per night from May 17 to May 18
$335 total
May 17 - May 18
Total with taxes and fees
A private beach, 3 restaurants, and 2 outdoor pools are all featured at this hotel. Enjoy beachfront dining and relax with beach cabanas and sun loungers. Families ...
Perfect for a few days! In such a good location to be able to explore a lot of places outside of the resort property and tucked away from the main road.

Reviewed on Apr 24, 2026

Opens in a new windowIslander Resort
Fairfield Inn & Suites by Marriott Marathon Florida Keys

Fairfield Inn & Suites by Marriott Marathon Florida Keys

3 out of 5
13201 Overseas Hwy Marathon FL
Fully refundableReserve now, pay when you stay
$179 nightly
The price is $201 total per night from May 3 to May 4
$201 total
May 3 - May 4
Total with taxes and fees
A marina, 2 outdoor pools, and a 24-hour gym are all featured at this traditional hotel. Traveling on business? Take advantage of the 24-hour business center ...
Great resort with all amenities. Pool, bar, restaurant all wonderful.

Reviewed on Apr 24, 2026

Opens in a new windowFairfield Inn & Suites by Marriott Marathon Florida Keys
Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

Three Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort

4 out of 5
84001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$322 nightly
The price is $362 total per night from May 25 to May 26
$362 total
May 25 - May 26
Total with taxes and fees
This Art Deco resort features a private beach, a marina, and 4 restaurants. Enjoy a day at the beach snorkeling, or relax with sun loungers. Families will appreciate ...
They hit you with a $65 per day resort fee…. Not the end of the world but not a good surprise after you leave.

Reviewed on Apr 21, 2026

Opens in a new windowThree Waters Resort and Marina, Islamorada, a Tribute Portfolio Resort
Amara Cay Resort

Amara Cay Resort

4 out of 5
80001 Overseas Hwy Islamorada FL
Fully refundableReserve now, pay when you stay
$249 nightly
The price is $280 total per night from May 4 to May 5
$280 total
May 4 - May 5
Total with taxes and fees
A private beach, 2 restaurants, and an outdoor pool are all featured at this resort. If you want to take your pet along, this pet-friendly property offers everything ...
Nice quiet, relaxing property

Reviewed on Apr 24, 2026

Opens in a new windowAmara Cay Resort
La Siesta Resort & Villas

La Siesta Resort & Villas

4 out of 5
80241 Overseas Highway Islamorada FL
Fully refundableReserve now, pay when you stay
$237 nightly
The price is $266 total per night from May 13 to May 14
$266 total
May 13 - May 14
Total with taxes and fees
The private beach and marina are among the highlights at this resort. Enjoy the outdoor pool and perks like a free area shuttle. There's a poolside bar on site, ...
It was simply stunning. Beautiful location, great facilities, spacious apartment and for a family of 5 the door key card being on the wristband is genius. Thank you for a wonderful stay

Reviewed on Apr 21, 2026

Opens in a new windowLa Siesta Resort & Villas
Hawks Cay Resort

Hawks Cay Resort

4 out of 5
61 Hawks Cay Blvd Marathon FL
Fully refundableReserve now, pay when you stay
$326 nightly
The price is $365 total per night from May 25 to May 26
$365 total
May 25 - May 26
Total with taxes and fees
This luxury hotel features a private beach, a full-service spa, and a marina. Spend a day at the beach snorkeling, or relax with sun loungers and beach umbrellas. ...
We had a fantastic stay at Hawks Cay, made even better by an unexpected upgrade to a villa. While the staff couldn't pinpoint exactly why the upgrade happened, it turned out to be the highlight of our trip. * The Villa Experience: Initially, I was concerned that staying in a villa would feel too ...

Reviewed on Apr 24, 2026

Opens in a new windowHawks Cay Resort
Don't see what you're looking for?
See all available properties in Lower Arsnicker Keys
View all properties
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Recent Lower Arsnicker Keys hotel reviews by fellow wanderers

Explore More Ways to Travel with Travelocity